BDBM50555388 CHEMBL4750705

SMILES CN(C)C(=O)c1cnc(Nc2cnc(cn2)C#N)cc1NCC1CCNCC1

InChI Key InChIKey=QPWHMDATXFXAQF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50555388   

TargetSerine/threonine-protein kinase Chk1(Human)
Sareum

Curated by ChEMBL
LigandPNGBDBM50555388(CHEMBL4750705)
Affinity DataIC50: 398nMAssay Description:Inhibition of CHK1 (unknown origin) using 5-FAM-KKKVSRSGLYRSPSMPENLNRPR-COOH peptide as substrate incubated for 1 hr in presence of ATP by caliper mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed