BDBM50559540 CHEMBL4750527

SMILES CCOc1ccc2nn(-c3ccc4nn(C)cc4c3)c(=O)c(-c3ccc(OC)cc3)c2n1

InChI Key InChIKey=IROSCZHDFQZJMT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50559540   

TargetS-adenosylmethionine synthase isoform type-2(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50559540(CHEMBL4750527)
Affinity DataIC50: <100nMAssay Description:Inhibition of MAT2A in human HCT-116 cells assessed as reduction in SAM incubated for 72 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetS-adenosylmethionine synthase isoform type-2(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50559540(CHEMBL4750527)
Affinity DataIC50: <100nMAssay Description:Inhibition of recombinant human MAT2A expressed in baculovirus infected Sf9 cells using L-methionine as substrate incubated for 60 mins followed by s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed