BDBM50565986 CHEMBL4789639

SMILES: [2H]C([2H])([2H])NC(=O)c1cnc(NC(=O)C2CC2)cc1Nc1cccc(-c2ncc(F)cn2)c1OC

InChI Key: InChIKey=BBRMAVGRWHNAIG-FIBGUPNXSA-N

Data: 1 KI  14 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 50565986   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Non-receptor tyrosine-protein kinase TYK2 (Human)	BDBM50565986 (CHEMBL4789639) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.190	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Non-receptor tyrosine-protein kinase TYK2 (Human)	BDBM50565986 (CHEMBL4789639) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
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Non-receptor tyrosine-protein kinase TYK2 (Human)	BDBM50565986 (CHEMBL4789639) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	58	n/a	n/a	n/a	n/a	n/a	n/a
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Non-receptor tyrosine-protein kinase TYK2 (Human)	BDBM50565986 (CHEMBL4789639) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
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Non-receptor tyrosine-protein kinase TYK2 [5-1181] (Mouse)	BDBM50565986 (CHEMBL4789639) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	481	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 1A2 (Human)	BDBM50565986 (CHEMBL4789639) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 3A4 (Human)	BDBM50565986 (CHEMBL4789639) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2B6 (Human)	BDBM50565986 (CHEMBL4789639) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C9 (Human)	BDBM50565986 (CHEMBL4789639) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2D6 (Human)	BDBM50565986 (CHEMBL4789639) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C19 (Human)	BDBM50565986 (CHEMBL4789639) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase JAK1 (Human)	BDBM50565986 (CHEMBL4789639) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.80	n/a	n/a	n/a	n/a	n/a	n/a
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JAK3/JAK1 (Human)	BDBM50565986 (CHEMBL4789639) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.25E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase JAK2 (Human)	BDBM50565986 (CHEMBL4789639) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Human)	BDBM50565986 (CHEMBL4789639) Show SMILES Show InChI	GoogleScholar	UniChem		0.0200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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