BDBM50569744 CHEMBL4874576

SMILES Cc1ccc2nc3CCCc3c(N)c2c1

InChI Key InChIKey=FUEAQDJAQZSMNY-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50569744   

TargetAcetylcholinesterase(Human)
University Hospital Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50569744(CHEMBL4874576)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant AChE assessed as reduction in cholinesterase activity using acetylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/alpha-6/beta-4(Rat)
University Hospital Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50569744(CHEMBL4874576)
Affinity DataIC50: 1.98E+4nMAssay Description:Inhibition of human GluN1a/GluN2B receptor expressed in HEK293 cells assessed as inhibition of glycine/glutamate-induced current measured at -60 mV h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
University Hospital Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50569744(CHEMBL4874576)
Affinity DataIC50: 2.05E+4nMAssay Description:Inhibition of human GluN1a/GluN2A receptor expressed in HEK293 cells assessed as inhibition of glycine/glutamate-induced current measured at -60 mV h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetCholinesterase(Human)
University Hospital Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50569744(CHEMBL4874576)
Affinity DataIC50: 2.37E+4nMAssay Description:Inhibition of human plasmatic BuChE assessed as reduction in cholinesterase activity by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed