BDBM50573330 CHEMBL4287130

SMILES COc1cccc(COc2c(oc3ccccc3c2=O)-c2ccc(OCCOCCN=[N+]=[N-])cc2)c1

InChI Key InChIKey=VVIGJSJSXWHMGZ-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50573330   

TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
Hong Kong Polytechnic University

Curated by ChEMBL
LigandPNGBDBM50573330(CHEMBL4287130)
Affinity DataEC50:  76nMAssay Description:Inhibition of BCRP (unknown origin) transfected in HEK293/R2 cells assessed as reversal of topotecan resistance after 5 days by MTS/PMS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed