BDBM50575930 CHEMBL4860934

SMILES COc1cccc(c1)S(=O)(=O)N(CC(O)=O)c1cccc(c1)-n1ncc(C(O)=O)c1[C@H]1C[C@@H]1c1ccccc1

InChI Key InChIKey=BLJRYRIUUYNZFT-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50575930   

TargetKelch-like ECH-associated protein 1(Human)
AstraZeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50575930BDBM50575930(CHEMBL4860934)
Affinity DataKi:  40nMAssay Description:Binding affinity to Keap1 Kelch domain (unknown origin) assessed as inhibition constant by fluorescence polarization analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50575930BDBM50575930(CHEMBL4860934)
Affinity DataKi:  40nMAssay Description:Inhibition of interaction between human KEAP1 Kelch domain/FAM-Nrf2 using Cy5-Nrf2 incubated for 10 to 15 mins by competitive fluorescence polarizati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed