BDBM50589122 CHEMBL5185708

SMILES NS(=O)(=O)c1ccc(CN2C(=O)c3ccc(cc3C2=O)C(O)=O)cc1

InChI Key InChIKey=OXXJZVWLYGJXOP-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50589122   

TargetCarbonic anhydrase 2(Human)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50589122(CHEMBL5185708)
Affinity DataKi:  26nMAssay Description:Binding affinity to human recombinant CA2 assessed as inhibition constant incubated for 10 mins prior to testing by phenol red based stopped-flow CO2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetCarbonic anhydrase 9(Human)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50589122(CHEMBL5185708)
Affinity DataKi:  54nMAssay Description:Binding affinity to human recombinant CA9 assessed as inhibition constant incubated for 10 mins prior to testing by phenol red based stopped-flow CO2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetCarbonic anhydrase 1(Human)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50589122(CHEMBL5185708)
Affinity DataKi:  54nMAssay Description:Binding affinity to human recombinant CA1 assessed as inhibition constant incubated for 10 mins prior to testing by phenol red based stopped-flow CO2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetCarbonic anhydrase 4(Human)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50589122(CHEMBL5185708)
Affinity DataKi:  317nMAssay Description:Binding affinity to human recombinant CA4 assessed as inhibition constant incubated for 10 mins prior to testing by phenol red based stopped-flow CO2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetCarbonic anhydrase 4(Human)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50589122(CHEMBL5185708)
Affinity DataKi:  317nMAssay Description:Binding affinity to human recombinant CA4 assessed as inhibition constant incubated for 10 mins prior to testing by phenol red based stopped-flow CO2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed