BDBM50590396 CHEMBL5172181

SMILES Cc1ccc(cc1C(=O)N[C@H](C)c2cccc3c2cccc3)NC(=O)C=C

InChI Key InChIKey=QMJFETCLZITVFG-UHFFFAOYSA-N

Data  2 IC50

PDB links: 2 PDB IDs match this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50590396   

TargetReplicase polyprotein 1ab(2019-nCoV)
Mazandaran University of Medical Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50590396BDBM50590396(CHEMBL5172181)
Affinity DataIC50: 6.40E+3nMAssay Description:Inhibition of SARS-CoV-2 PLpro expressed in Escherichia coli BL21(DE3)-Gold strain using LKGGAMC as substrate preincubated for 5 mins followed by sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Mazandaran University of Medical Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50590396BDBM50590396(CHEMBL5172181)
Affinity DataIC50: 6.40E+3nMAssay Description:Inhibition of SARS-CoV-2 papain-like protease nsp3 expressed in Escherichia coli BL21 (DE3) using LKGG-AMC probe as substrate by fluorescence based b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details Article
PubMed