BDBM50591705 CHEMBL5175274

SMILES Cc1nc2cc(F)ccc2[nH]c1=O

InChI Key InChIKey=XSHAHALIPDPMMT-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50591705   

TargetATP-dependent translocase ABCB1(Human)
Central South University

Curated by ChEMBL
LigandPNGBDBM50591705(CHEMBL5175274)
Affinity DataIC50: 561nMAssay Description:Inhibition of P-gp in human K562 cells assessed as adriamycin IC50 at 10 ug/mlMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetATP-dependent translocase ABCB1(Human)
Central South University

Curated by ChEMBL
LigandPNGBDBM50591705(CHEMBL5175274)
Affinity DataIC50: 673nMAssay Description:Inhibition of P-gp in human K562 cells assessed as adriamycin IC50 at 4 ug/mlMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetATP-dependent translocase ABCB1(Human)
Central South University

Curated by ChEMBL
LigandPNGBDBM50591705(CHEMBL5175274)
Affinity DataIC50: 729nMAssay Description:Inhibition of P-gp in human K562 cells assessed as adriamycin IC50 at 8 ug/mlMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetATP-dependent translocase ABCB1(Human)
Central South University

Curated by ChEMBL
LigandPNGBDBM50591705(CHEMBL5175274)
Affinity DataIC50: 785nMAssay Description:Inhibition of P-gp in human K562 cells assessed as adriamycin IC50 at 2 ug/mlMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetATP-dependent translocase ABCB1(Human)
Central South University

Curated by ChEMBL
LigandPNGBDBM50591705(CHEMBL5175274)
Affinity DataIC50: 841nMAssay Description:Inhibition of P-gp in human K562 cells assessed as adriamycin IC50 at 6 ug/mlMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetATP-dependent translocase ABCB1(Human)
Central South University

Curated by ChEMBL
LigandPNGBDBM50591705(CHEMBL5175274)
Affinity DataIC50: 5.78E+3nMAssay Description:Inhibition of P-gp in human K562/A02 cells assessed as adriamycin IC50 at 8 ug/mlMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetATP-dependent translocase ABCB1(Human)
Central South University

Curated by ChEMBL
LigandPNGBDBM50591705(CHEMBL5175274)
Affinity DataIC50: 6.28E+3nMAssay Description:Inhibition of P-gp in human K562/A02 cells assessed as adriamycin IC50 at 10 ug/mlMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetATP-dependent translocase ABCB1(Human)
Central South University

Curated by ChEMBL
LigandPNGBDBM50591705(CHEMBL5175274)
Affinity DataIC50: 7.52E+3nMAssay Description:Inhibition of P-gp in human K562/A02 cells assessed as adriamycin IC50 at 6 ug/mlMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetATP-dependent translocase ABCB1(Human)
Central South University

Curated by ChEMBL
LigandPNGBDBM50591705(CHEMBL5175274)
Affinity DataIC50: 9.03E+3nMAssay Description:Inhibition of P-gp in human K562/A02 cells assessed as adriamycin IC50 at 4 ug/mlMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetATP-dependent translocase ABCB1(Human)
Central South University

Curated by ChEMBL
LigandPNGBDBM50591705(CHEMBL5175274)
Affinity DataIC50: 1.29E+4nMAssay Description:Inhibition of P-gp in human K562/A02 cells assessed as adriamycin IC50 at 2 ug/mlMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed