BDBM50594834 CHEMBL5178409

SMILES [H][C@@]12C[C@@]([H])([C@H](CC)CN1CC[C@@]1(O)C2Nc2cccc(OC)c12)C(=C/OC)\C(=O)OC

InChI Key InChIKey=QXFXDJATKPXTFF-UHFFFAOYSA-N

Data  5 KI  4 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50594834   

TargetMu-type opioid receptor(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50594834(CHEMBL5178409)
Affinity DataKi:  11nMAssay Description:Displacement of [3H]DAMGO from guinea pig brain membrane MOP incubated for 1 hr by scintillation counter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50594834(CHEMBL5178409)
Affinity DataEC50:  35nMAssay Description:Agonist activity at MOP (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50594834(CHEMBL5178409)
Affinity DataKi:  47nMAssay Description:Binding affinity to MOP (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetKappa-type opioid receptor(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50594834(CHEMBL5178409)
Affinity DataKi:  85nMAssay Description:Displacement of [3H]U69593 from guinea pig brain membrane KOP incubated for 1 hr by scintillation counter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetKappa-type opioid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50594834(CHEMBL5178409)
Affinity DataKi:  188nMAssay Description:Binding affinity to KOP (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetDelta-type opioid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50594834(CHEMBL5178409)
Affinity DataKi:  219nMAssay Description:Binding affinity to DOP (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetKappa-type opioid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50594834(CHEMBL5178409)
Affinity DataIC50: 691nMAssay Description:Inhibition of KOP (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetDelta-type opioid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50594834(CHEMBL5178409)
Affinity DataIC50: 2.52E+3nMAssay Description:Inhibition of DOP (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetKappa-type opioid receptor(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50594834(CHEMBL5178409)
Affinity DataIC50: 7.90E+3nMAssay Description:Inhibition of mouse KOPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetDelta-type opioid receptor(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50594834(CHEMBL5178409)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of mouse DOPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed