BDBM50598853 CHEMBL5169330::US20240207300, Compound 285

SMILES Cc1cnc2n(c(N)c(C(N)=O)c2n1)-c1c(C)ccc(O)c1C

InChI Key InChIKey=WHYJZCBTMCZRNS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50598853   

TargetMyelin transcription factor 1(Human)
Repare Therapeutics

US Patent
LigandPNGBDBM50598853(CHEMBL5169330 | US20240207300, Compound 285 | US12...)
Affinity DataIC50: 11nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetMyelin transcription factor 1(Human)
Repare Therapeutics

US Patent
LigandPNGBDBM50598853(CHEMBL5169330 | US20240207300, Compound 285 | US12...)
Affinity DataIC50: 11nMAssay Description:Detection of Myt1 kinase activity utilized a recombinant human Myt1 kinase assay measuring the hydrolysis of ATP using a commercially available ADP-G...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

LigandPNGBDBM50598853(CHEMBL5169330 | US20240207300, Compound 285 | US12...)
Affinity DataIC50: 108nMAssay Description:Inhibition of N-terminal recombinant PKMYT1 (76 to 362 residues) in CCNE1 amplified human FU-OV-1 cells assessed as phosphorylation of CDK1 at Thr14 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed