BDBM50612391 CHEMBL5284733

SMILES OC(=O)c1ccccc1-c1ccc(Cn2ccc(OCc3c(noc3-c3cccs3)-c3ccccc3Cl)n2)cc1

InChI Key InChIKey=NXQKRWNUFQHJDF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50612391   

TargetBile acid receptor(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50612391(CHEMBL5284733)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at FXR (unknown origin) by HTFR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetBile acid receptor(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50612391(CHEMBL5284733)
Affinity DataIC50: 1.22E+4nMAssay Description:Antagonist activity at FXR in human HepG2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed