BDBM50615224 CHEMBL5272583

SMILES CC(C)[C@H]1COC(=O)N1c1ccnc(NC(C)c2ccccc2)n1

InChI Key InChIKey=CUTPLPKYQGWUBC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50615224   

TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50615224(CHEMBL5272583)
Affinity DataIC50: 800nMAssay Description:Inhibition of human N-terminal 6His-tagged IDH1 R132H mutant expressed in Escherichia coli Rosetta2 (DE3) assessed as effect on intracellular 2-HG le...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed