BindingDB logo
myBDB logout

BDBM50773 1-[4-(2-methoxyphenyl)-1-piperazinyl]-3-(1-naphthalenyloxy)-2-propanol;hydrochloride::1-[4-(2-methoxyphenyl)piperazin-1-yl]-3-naphthalen-1-yloxy-propan-2-ol;hydrochloride::1-[4-(2-methoxyphenyl)piperazin-1-yl]-3-naphthalen-1-yloxypropan-2-ol;hydrochloride::1-[4-(2-methoxyphenyl)piperazino]-3-(1-naphthoxy)propan-2-ol;hydrochloride::CHEMBL142635::MLS000069363::NAFTOPIDIL DIHYDROCHLORIDE::SMR000058489::cid_4418::cid_6603044

SMILES: COc1ccccc1N1CCN(CC(O)COc2cccc3ccccc23)CC1

InChI Key: InChIKey=HRRBJVNMSRJFHQ-UHFFFAOYSA-N

Data: 10 KI  8 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 19 hits for monomerid = 50773   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Voltage-dependent T-type calcium channel subunit alpha-1H


(Human)
BDBM50773
PNG
(1-[4-(2-methoxyphenyl)piperazin-1-yl]-3-naphthalen...)
GoogleScholar
UniChem
n/an/an/an/a 3.72E+3n/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Bile salt export pump


(Human)
BDBM50773
PNG
(1-[4-(2-methoxyphenyl)piperazin-1-yl]-3-naphthalen...)
GoogleScholar
UniChem
n/an/a<1.00E+4n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Glycoprotein 42


(HHV-4)
BDBM50773
PNG
(1-[4-(2-methoxyphenyl)piperazin-1-yl]-3-naphthalen...)
GoogleScholar
UniChem
n/an/a 1.41E+4n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Alpha-1A adrenergic receptor


(Human)
BDBM50773
PNG
(1-[4-(2-methoxyphenyl)piperazin-1-yl]-3-naphthalen...)
GoogleScholar
UniChem
n/an/a 555n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Alpha-1B adrenergic receptor


(Human)
BDBM50773
PNG
(1-[4-(2-methoxyphenyl)piperazin-1-yl]-3-naphthalen...)
GoogleScholar
UniChem
n/an/a 634n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Alpha-1A adrenergic receptor


(Human)
BDBM50773
PNG
(1-[4-(2-methoxyphenyl)piperazin-1-yl]-3-naphthalen...)
GoogleScholar
UniChem
n/an/a 555n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Alpha-1D adrenergic receptor


(Human)
BDBM50773
PNG
(1-[4-(2-methoxyphenyl)piperazin-1-yl]-3-naphthalen...)
GoogleScholar
UniChem
n/an/a 55n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Alpha-1B adrenergic receptor


(Human)
BDBM50773
PNG
(1-[4-(2-methoxyphenyl)piperazin-1-yl]-3-naphthalen...)
GoogleScholar
UniChem
n/an/a 634n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Alpha-1D adrenergic receptor


(Human)
BDBM50773
PNG
(1-[4-(2-methoxyphenyl)piperazin-1-yl]-3-naphthalen...)
GoogleScholar
UniChem
n/an/a 55n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Alpha-1D adrenergic receptor


(Human)
BDBM50773
PNG
(1-[4-(2-methoxyphenyl)piperazin-1-yl]-3-naphthalen...)
GoogleScholar
UniChem
1.20n/an/an/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Alpha-1A adrenergic receptor


(Human)
BDBM50773
PNG
(1-[4-(2-methoxyphenyl)piperazin-1-yl]-3-naphthalen...)
GoogleScholar
UniChem
3.70n/an/an/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Alpha-1A adrenergic receptor


(Human)
BDBM50773
PNG
(1-[4-(2-methoxyphenyl)piperazin-1-yl]-3-naphthalen...)
GoogleScholar
UniChem
3.70n/an/an/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Alpha-1A adrenergic receptor


(Human)
BDBM50773
PNG
(1-[4-(2-methoxyphenyl)piperazin-1-yl]-3-naphthalen...)
GoogleScholar
UniChem
5.90n/an/an/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Alpha-1A adrenergic receptor


(Human)
BDBM50773
PNG
(1-[4-(2-methoxyphenyl)piperazin-1-yl]-3-naphthalen...)
GoogleScholar
UniChem
5.90n/an/an/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Alpha-1B adrenergic receptor


(Human)
BDBM50773
PNG
(1-[4-(2-methoxyphenyl)piperazin-1-yl]-3-naphthalen...)
GoogleScholar
UniChem
20n/an/an/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor


(Rat)
BDBM50773
PNG
(1-[4-(2-methoxyphenyl)piperazin-1-yl]-3-naphthalen...)
GoogleScholar
UniChem
39n/an/an/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Beta-2 adrenergic receptor


(Dog)
BDBM50773
PNG
(1-[4-(2-methoxyphenyl)piperazin-1-yl]-3-naphthalen...)
GoogleScholar
UniChem
1.00E+3n/an/an/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Beta-1 adrenergic receptor


(Rat)
BDBM50773
PNG
(1-[4-(2-methoxyphenyl)piperazin-1-yl]-3-naphthalen...)
GoogleScholar
UniChem
>1.00E+3n/an/an/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor


(Rat)
BDBM50773
PNG
(1-[4-(2-methoxyphenyl)piperazin-1-yl]-3-naphthalen...)
GoogleScholar
UniChem
1.60E+3n/an/an/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair