BDBM507736 (R)-7-chloro-4-(3-fluoropyrrolidin-1- yl)-1-phenylquinazolin-2(1H)-one::US11046691, Compound 80::US11084798, Cpd No 80::US11130759, Cpd. No. 80

SMILES: c1ccc(cc1)N2c3cc(ccc3C(=NC2=O)N4CC[C@H](C4)F)Cl

InChI Key: InChIKey=GPTUSHRRTGGGTD-UHFFFAOYSA-N

Data: 7 IC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 507736   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
S-adenosylmethionine synthase isoform type-2 (Human)	BDBM507736 (US11130759, Cpd. No. 80 | US11046691, Compound 80 ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<200	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
S-adenosylmethionine synthase isoform type-2 (Human)	BDBM507736 (US11130759, Cpd. No. 80 | US11046691, Compound 80 ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<200	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
S-adenosylmethionine synthase isoform type-2 (Human)	BDBM507736 (US11130759, Cpd. No. 80 | US11046691, Compound 80 ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<200	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
S-adenosylmethionine synthase isoform type-2 (Human)	BDBM507736 (US11130759, Cpd. No. 80 | US11046691, Compound 80 ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<200	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
S-adenosylmethionine synthase isoform type-2 (Human)	BDBM507736 (US11130759, Cpd. No. 80 | US11046691, Compound 80 ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<200	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
S-adenosylmethionine synthase isoform type-2 (Human)	BDBM507736 (US11130759, Cpd. No. 80 | US11046691, Compound 80 ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
S-adenosylmethionine synthase isoform type-1 (Homo sapiens)	BDBM507736 (US11130759, Cpd. No. 80 | US11046691, Compound 80 ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	813	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair