BDBM5078 1,2,4-Oxadiazole Analogue 8::4-[(2S)-2-acetamido-2-{[2-(3-{[4-(trifluoromethyl)phenyl]methyl}-1,2,4-oxadiazol-5-yl)ethyl]carbamoyl}ethyl]phenoxyphosphonic acid

SMILES CC(=O)N[C@@H](Cc1ccc(OP(O)(O)=O)cc1)C(=O)NCCc1nc(Cc2ccc(cc2)C(F)(F)F)no1

InChI Key InChIKey=ITJVFFJIFZONRZ-IBGZPJMESA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 5078   

TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Ariad Pharmaceuticals

LigandPNGBDBM5078(1,2,4-Oxadiazole Analogue 8 | 4-[(2S)-2-acetamido-...)
Affinity DataIC50: >5.00E+5nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Ariad Pharmaceuticals

LigandPNGBDBM5078(1,2,4-Oxadiazole Analogue 8 | 4-[(2S)-2-acetamido-...)
Affinity DataIC50: >5.00E+5nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Ariad Pharmaceuticals

LigandPNGBDBM5078(1,2,4-Oxadiazole Analogue 8 | 4-[(2S)-2-acetamido-...)
Affinity DataIC50: >5.00E+5nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed