BDBM511910 (1R,3S,5R)-2-(2-(3- acetyl-5-(2- methylpyrimidin-5- yl)-1H-pyrazolo[3,4- c]pyridin-1-yl)acetyl)- N-(6-bromo-3- methylpyridin-2-yl)-5- (((3aR,6a5)- hexahydrocyclopenta [c]pyrrol-2(1H)- yl)methyl)-2- azabicyclo[3.1.0]hexane- 3-carboxamide::US11084800, Cpd No. 245::US11708351, Compound 245

SMILES CC(=O)c1nn(CC(=O)N2[C@@H]3C[C@]3(CN3C[C@@H]4CCC[C@@H]4C3)C[C@H]2C(=O)Nc2nc(Br)ccc2C)c2cnc(cc12)-c1cnc(C)nc1

InChI Key InChIKey=CLLJFZPJLXFLDT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 511910   

TargetComplement factor D(Human)
Achillion Pharmaceuticals

US Patent
LigandPNGBDBM511910(US11084800, Cpd No. 245 | (1R,3S,5R)-2-(2-(3- acet...)
Affinity DataIC50: 1.00E+3nMAssay Description:Human Factor D (purified from human serum, Complement Technology, Inc.) at 80 nM final concentration is incubated with test compound at various conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2022
Entry Details
US Patent

TargetComplement factor D(Human)
Achillion Pharmaceuticals

US Patent
LigandPNGBDBM511910(US11084800, Cpd No. 245 | (1R,3S,5R)-2-(2-(3- acet...)
Affinity DataIC50: 1.00E+3nMAssay Description:Human Factor D (purified from human serum, Complement Technology, Inc.) at 80 nM final concentration is incubated with test compound at various conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2023
Entry Details
US Patent