BDBM51305 3,5-diphenyl-2-(trifluoromethyl)-1H-pyrazolo[1,5-a]pyrimidin-7-one::3,5-diphenyl-2-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-7(4H)-one::CHEMBL522946::MLS000850151::SMR000456169::cid_2810970

SMILES: c1ccc(cc1)C2=CC(=O)N3C(=N2)C(=C(N3)C(F)(F)F)c4ccccc4

InChI Key: InChIKey=OOAHQJLYDSAULT-UHFFFAOYSA-N

Data: 5 IC50

PDB links: 2 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 51305   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycoprotein 42 (HHV-4)	BDBM51305 (SMR000456169 | 3,5-diphenyl-2-(trifluoromethyl)pyr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.03E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase JAK2 (Human)	BDBM51305 (SMR000456169 | 3,5-diphenyl-2-(trifluoromethyl)pyr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase JAK2 (Human)	BDBM51305 (SMR000456169 | 3,5-diphenyl-2-(trifluoromethyl)pyr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Non-receptor tyrosine-protein kinase TYK2 (Human)	BDBM51305 (SMR000456169 | 3,5-diphenyl-2-(trifluoromethyl)pyr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
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1-deoxy-D-xylulose-5-phosphate synthase (Mycobacterium tuberculosis (strain ATCC 25618 / H3...)	BDBM51305 (SMR000456169 | 3,5-diphenyl-2-(trifluoromethyl)pyr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
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