BDBM5152 (2E)-2-cyano-N-{4-[(2E)-2-cyano-3-(3,4,5-trihydroxyphenyl)prop-2-enamido]butyl}-3-(3,4,5-trihydroxyphenyl)prop-2-enamide::CHEMBL358746::Dimeric Tyrphostin 5

SMILES Oc1cc(\C=C(/C#N)C(=O)NCCCCNC(=O)C(=C\c2cc(O)c(O)c(O)c2)\C#N)cc(O)c1O

InChI Key InChIKey=ZJGWOFFIHTYMCZ-IAGONARPSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 5152   

TargetDynamin-1(Homo sapiens (Human))
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM5152((2E)-2-cyano-N-{4-[(2E)-2-cyano-3-(3,4,5-trihydrox...)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibitory activity against dynamin1 GTPase expressed in sheep brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University Of Jerusalem

LigandPNGBDBM5152((2E)-2-cyano-N-{4-[(2E)-2-cyano-3-(3,4,5-trihydrox...)
Affinity DataIC50:  600nMpH: 7.6 T: 2°CAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed