BDBM5165 (2E)-3-(3-bromo-4,5-dihydroxyphenyl)-2-{[(1E)-2-(3-bromo-4,5-dihydroxyphenyl)-1-cyanoeth-1-ene-1-]sulfonyl}prop-2-enenitrile::Dimeric Tyrphostin 23

SMILES Oc1cc(\C=C(/C#N)S(=O)(=O)C(=C\c2cc(O)c(O)c(Br)c2)\C#N)cc(Br)c1O

InChI Key InChIKey=VBOBOVYYRHVGSJ-NJDSBKIZSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 5165   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University Of Jerusalem

LigandPNGBDBM5165((2E)-3-(3-bromo-4,5-dihydroxyphenyl)-2-{[(1E)-2-(3...)
Affinity DataIC50:  850nMpH: 7.6 T: 2°CAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed