BindingDB PrimarySearch_ki

Search and Browse
- Target
- Compound
- Special tools
- Citation
- Special Data Sets
- Other Databases
  - PDB 85% 100% Seq ID
  - UniProtKB/Swiss-Prot
  - UniProtKB/TrEMBL
  - PubMed
Download
- All Compounds & Data
- Target Names &
  - Ki IC50 Kd EC50
  - ΔG° ΔH° -TΔS°
Enter Data

BDBM5171 (2E)-2-[(3,4-dihydroxyphenyl)carbonyl]-3-(1H-indol-3-yl)prop-2-enenitrile::Indole-Containing Inhibitor 5

SMILES: Oc1ccc(cc1O)C(=O)C(=C\c1c[nH]c2ccccc12)\C#N

InChI Key: InChIKey=TTZDOBVWBQXGDC-UHFFFAOYSA-N

Data: 4 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 5171
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Epidermal growth factor receptor (Human)	BDBM5171 ((2E)-2-[(3,4-dihydroxyphenyl)carbonyl]-3-(1H-indol...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a	7.5	4
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Human)	BDBM5171 ((2E)-2-[(3,4-dihydroxyphenyl)carbonyl]-3-(1H-indol...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Protein-tyrosine kinase 6 (Human)	BDBM5171 ((2E)-2-[(3,4-dihydroxyphenyl)carbonyl]-3-(1H-indol...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.32E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Protein-tyrosine kinase 6 (Human)	BDBM5171 ((2E)-2-[(3,4-dihydroxyphenyl)carbonyl]-3-(1H-indol...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.32E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair