BDBM5173 (2E)-2-cyano-3-(1H-indol-3-yl)prop-2-enethioamide::Indole-Containing Inhibitor 7

SMILES NC(=S)C(=C\c1c[nH]c2ccccc12)\C#N

InChI Key InChIKey=YGJSREKVWCOLRY-VMPITWQZSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 5173   

TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM5173((2E)-2-cyano-3-(1H-indol-3-yl)prop-2-enethioamide ...)
Affinity DataIC50:  6.50E+3nMAssay Description:The assay was using Swiss 3T3 cell membranes harboring EGF-R or PDGFR-beta. Receptor autophosphorylation was initiated by addition of [gamma-32P]ATP ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM5173((2E)-2-cyano-3-(1H-indol-3-yl)prop-2-enethioamide ...)
Affinity DataIC50:  6.50E+4nMpH: 7.5 T: 2°CAssay Description:The assay was using Swiss 3T3 cell membranes harboring EGF-R or PDGFR-beta. Receptor autophosphorylation was initiated by addition of [gamma-32P]ATP ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed