BDBM518406 2-[4-[2-[(2S)-2-Methylazetidin-1-yl]-6-(trifluoromethyl)pyrimidin-4-yl]pyrazol-1-yl]-1-piperazin-1-yl-ethanone::US11124500, Example 1

SMILES: C[C@H]1CCN1c1nc(cc(n1)C(F)(F)F)-c1cnn(CC(=O)N2CCNCC2)c1

InChI Key: InChIKey=HAUDFIFEGDNKJX-UHFFFAOYSA-N

Data: 5 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 518406   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ketohexokinase (Human)	BDBM518406 (US11124500, Example 1 | 2-[4-[2-[(2S)-2-Methylazet...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	20.7	n/a	n/a	n/a	n/a	n/a	n/a
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Isoform A of Ketohexokinase (Peripheral) (Human)	BDBM518406 (US11124500, Example 1 | 2-[4-[2-[(2S)-2-Methylazet...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	24.2	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Ketohexokinase (Human)	BDBM518406 (US11124500, Example 1 | 2-[4-[2-[(2S)-2-Methylazet...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Ketohexokinase (Human)	BDBM518406 (US11124500, Example 1 | 2-[4-[2-[(2S)-2-Methylazet...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Ketohexokinase (Human)	BDBM518406 (US11124500, Example 1 | 2-[4-[2-[(2S)-2-Methylazet...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair