BindingDB logo
myBDB logout

BDBM51908 (6-bromo-2-methyl-4-quinolyl)-(p-anisylideneamino)amine::6-bromanyl-N-[(4-methoxyphenyl)methylideneamino]-2-methyl-quinolin-4-amine::6-bromo-N-[(4-methoxyphenyl)methylideneamino]-2-methyl-4-quinolinamine::6-bromo-N-[(4-methoxyphenyl)methylideneamino]-2-methylquinolin-4-amine::MLS001213250::SMR000542948::cid_4402133

InChI string: InChI=1S/C18H16BrN3O/c1-12-9-18(16-10-14(19)5-8-17(16)21-12)22-20-11-13-3-6-15(23-2)7-4-13/h3-10H,11H2,1-2H3

SMILES: COc1ccc(CN=Nc2cc(C)nc3ccc(Br)cc23)cc1

InChI Key: InChIKey=BQIAOAGYKNPKBN-UHFFFAOYSA-N

Data: 1 IC50  3 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 51908   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Mitogen-activated protein kinase 2


(Homo sapiens)
BDBM51908
PNG
((6-bromo-2-methyl-4-quinolyl)-(p-anisylideneamino)...)
Show SMILES COc1ccc(CN=Nc2cc(C)nc3ccc(Br)cc23)cc1
Show InChI InChI=1S/C18H16BrN3O/c1-12-9-18(16-10-14(19)5-8-17(16)21-12)22-20-11-13-3-6-15(23-2)7-4-13/h3-10H,11H2,1-2H3
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PCBioAssay
n/an/an/an/a 8.32E+3n/an/an/an/a



NMMLSC

Curated by PubChem BioAssay


Assay Description
University of New Mexico Assay Overview: Assay Support: 1R03MH084830-01 Project Title: TR-FRET HTS Assay for Inhibitors of MEKK2-MEK5 PB1 Domain...


Citation and Details
More data for this
Ligand-Target Pair
ubiquitin-conjugating enzyme E2 N


(Homo sapiens)
BDBM51908
PNG
((6-bromo-2-methyl-4-quinolyl)-(p-anisylideneamino)...)
Show SMILES COc1ccc(CN=Nc2cc(C)nc3ccc(Br)cc23)cc1
Show InChI InChI=1S/C18H16BrN3O/c1-12-9-18(16-10-14(19)5-8-17(16)21-12)22-20-11-13-3-6-15(23-2)7-4-13/h3-10H,11H2,1-2H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
PCBioAssay
n/an/a>2.00E+4n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego CA...


PubChem Bioassay (2011)

More data for this
Ligand-Target Pair
Hsf1 protein


(Mus musculus)
BDBM51908
PNG
((6-bromo-2-methyl-4-quinolyl)-(p-anisylideneamino)...)
Show SMILES COc1ccc(CN=Nc2cc(C)nc3ccc(Br)cc23)cc1
Show InChI InChI=1S/C18H16BrN3O/c1-12-9-18(16-10-14(19)5-8-17(16)21-12)22-20-11-13-3-6-15(23-2)7-4-13/h3-10H,11H2,1-2H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
PCBioAssay
n/an/an/an/a>2.60E+5n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...


PubChem Bioassay (2010)

More data for this
Ligand-Target Pair
Mitogen-activated protein kinase 2


(Homo sapiens)
BDBM51908
PNG
((6-bromo-2-methyl-4-quinolyl)-(p-anisylideneamino)...)
Show SMILES COc1ccc(CN=Nc2cc(C)nc3ccc(Br)cc23)cc1
Show InChI InChI=1S/C18H16BrN3O/c1-12-9-18(16-10-14(19)5-8-17(16)21-12)22-20-11-13-3-6-15(23-2)7-4-13/h3-10H,11H2,1-2H3
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PCBioAssay
n/an/an/an/a 1.94E+3n/an/an/an/a



NMMLSC

Curated by PubChem BioAssay


Assay Description
University of New Mexico Assay Overview: Assay Support: 1R03MH084830-01 Project Title: TR-FRET HTS Assay for Inhibitors of MEKK2-MEK5 PB1 Domain...


Citation and Details
More data for this
Ligand-Target Pair