BDBM522987 1-(4-(4-amino-7- cyclopropyl-7H- pyrrolo[2,3- d]pyrimidin-5-yl)-2- fluorophenyl)-3-(5-(1- (trifluoromethyl)cyclopropyl)isoxazol- 3-yl)urea::US11161852, Compound 10::US11713321, Example 10

SMILES: Nc1ncnc2n(cc(-c3ccc(NC(=O)Nc4cc(on4)C4(CC4)C(F)(F)F)c(F)c3)c12)C1CC1

InChI Key: InChIKey=MJUUWYZZPRAKCW-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 522987   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase Nek7 (Human)	BDBM522987 (US11161852, Compound 10 | 1-(4-(4-amino-7- cyclopr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	225	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Nek7 (Human)	BDBM522987 (US11161852, Compound 10 | 1-(4-(4-amino-7- cyclopr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	225	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair