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BDBM53483 4-Methyl-N-[N'-(3-nitro-benzoyl)-hydrazinocarbothioyl]-benzamide::4-methyl-N-[[(3-nitrobenzoyl)amino]carbamothioyl]benzamide::4-methyl-N-[[(3-nitrobenzoyl)amino]thiocarbamoyl]benzamide::4-methyl-N-[[(3-nitrophenyl)carbonylamino]carbamothioyl]benzamide::4-methyl-N-[[[(3-nitrophenyl)-oxomethyl]hydrazo]-sulfanylidenemethyl]benzamide::MLS001210725::O-acyl oxime isatin derivative, 20::SMR000517394::cid_3138334

SMILES: Cc1ccc(cc1)C(=O)NC(=S)NNC(=O)c1cccc(c1)[N+]([O-])=O

InChI Key: InChIKey=ICDBHDROFOMQCO-UHFFFAOYSA-N

Data: 1 IC50  2 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 53483   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (UCH-L1)


(Mus musculus (Mouse))
BDBM53483
PNG
(4-Methyl-N-[N'-(3-nitro-benzoyl)-hydrazinocarb...)
Show SMILES Cc1ccc(cc1)C(=O)NC(=S)NNC(=O)c1cccc(c1)[N+]([O-])=O
Show InChI InChI=1S/C16H14N4O4S/c1-10-5-7-11(8-6-10)14(21)17-16(25)19-18-15(22)12-3-2-4-13(9-12)20(23)24/h2-9H,1H3,(H,18,22)(H2,17,19,21,25)
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MMDB

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PC sid
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Article
PubMed
n/an/a 3.60E+4n/an/an/an/a7.625



Brigham and Women's Hospital



Assay Description
Inhibition activity and selectivity for UCH-L1 and UCH-L3.


Chem Biol 10: 837-46 (2003)


Article DOI: 10.1016/j.chembiol.2003.08.010
BindingDB Entry DOI: 10.7270/Q20Z71P9
More data for this
Ligand-Target Pair
corticotropin releasing factor-binding protein


(Homo sapiens (Human))
BDBM53483
PNG
(4-Methyl-N-[N'-(3-nitro-benzoyl)-hydrazinocarb...)
Show SMILES Cc1ccc(cc1)C(=O)NC(=S)NNC(=O)c1cccc(c1)[N+]([O-])=O
Show InChI InChI=1S/C16H14N4O4S/c1-10-5-7-11(8-6-10)14(21)17-16(25)19-18-15(22)12-3-2-4-13(9-12)20(23)24/h2-9H,1H3,(H,18,22)(H2,17,19,21,25)
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antibodypedia
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PCBioAssay
n/an/an/an/a 2.89E+3n/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


PubChem Bioassay (2012)


Article DOI: 10.1038/nchembio.2085
BindingDB Entry DOI: 10.7270/Q2VX0F3D
More data for this
Ligand-Target Pair
streptokinase A precursor


(Streptococcus pyogenes M1 GAS)
BDBM53483
PNG
(4-Methyl-N-[N'-(3-nitro-benzoyl)-hydrazinocarb...)
Show SMILES Cc1ccc(cc1)C(=O)NC(=S)NNC(=O)c1cccc(c1)[N+]([O-])=O
Show InChI InChI=1S/C16H14N4O4S/c1-10-5-7-11(8-6-10)14(21)17-16(25)19-18-15(22)12-3-2-4-13(9-12)20(23)24/h2-9H,1H3,(H,18,22)(H2,17,19,21,25)
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n/an/an/an/a 1.50E+5n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: Group A streptococcus, GAS, streptokinase, expression, virulence, inhibition, dose response, EC50 Assay Overview: The goal of this assa...


PubChem Bioassay (2009)


BindingDB Entry DOI: 10.7270/Q2736PBV
More data for this
Ligand-Target Pair