BDBM54362 1-[3-(dimethylsulfamoyl)phenyl]-3-(5-isoquinolinyl)thiourea::1-[3-(dimethylsulfamoyl)phenyl]-3-(5-isoquinolyl)thiourea::1-[3-(dimethylsulfamoyl)phenyl]-3-isoquinolin-5-yl-thiourea::1-[3-(dimethylsulfamoyl)phenyl]-3-isoquinolin-5-ylthiourea::MLS000775933::SMR000371056::cid_4639178

SMILES: CN(C)S(=O)(=O)c1cccc(NC(=S)Nc2cccc3cnccc23)c1

InChI Key: InChIKey=YJDNIGRFMJSDIZ-UHFFFAOYSA-N

Data: 2 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 54362   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nucleotide-binding oligomerization domain-containing protein 2 (Human)	BDBM54362 (SMR000371056 | MLS000775933 | 1-[3-(dimethylsulfam...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.64E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Nucleotide-binding oligomerization domain-containing protein 1 (Human)	BDBM54362 (SMR000371056 | MLS000775933 | 1-[3-(dimethylsulfam...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.06E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tumor necrosis factor (Human)	BDBM54362 (SMR000371056 | MLS000775933 | 1-[3-(dimethylsulfam...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.39E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair