BDBM545 4-cyano-N-(3-{1-[4-hydroxy-2-oxo-6-(2-phenylethyl)-6-propyl-5,6-dihydro-2H-pyran-3-yl]propyl}phenyl)benzene-1-sulfonamide::CHEMBL21281::Sulfonamide-Containing 5,6-Dihydro-4-hydroxy-2-pyrones::Tipranavir analog 2

SMILES: CCCC1(CCc2ccccc2)CC(=O)C(C(CC)c2cccc(NS(=O)(=O)c3ccc(cc3)C#N)c2)C(=O)O1

InChI Key: InChIKey=BQKCUXNGMWFRMA-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 545   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dimer of Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1)	BDBM545 (4-cyano-N-(3-{1-[4-hydroxy-2-oxo-6-(2-phenylethyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		8	-10.9	n/a	n/a	n/a	n/a	n/a	5.0	22
TBA									Citation and Details
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1)	BDBM545 (4-cyano-N-(3-{1-[4-hydroxy-2-oxo-6-(2-phenylethyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dimer of Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1)	BDBM545 (4-cyano-N-(3-{1-[4-hydroxy-2-oxo-6-(2-phenylethyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		8.20	-10.9	n/a	n/a	n/a	n/a	n/a	5.0	22
TBA									Citation and Details
					More data for this Ligand-Target Pair