BDBM545113 US11286268, Compound 598

SMILES Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cnc(cc3c2=O)C#N)c2scc(C(=O)NS(C)(=O)=O)c2n1

InChI Key InChIKey=NVSDWGNLSLSUNI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 545113   

TargetEukaryotic translation initiation factor 4E-binding protein 1(Human)
Effector Therapeutics

US Patent
LigandPNGBDBM545113(US11286268, Compound 598)
Affinity DataIC50: 57.2nMAssay Description:eIF4E protein was pre-incubated with EDA-m7GDP-ATTO-550 in FPB at 2xconcentrations for 5 minutes prior to the addition of compounds. Compounds (100x)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2022
Entry Details
US Patent