BDBM545254 US11286268, Compound 742::US11286268, Compound 898

SMILES Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3c(C)nc(C4CC4)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

InChI Key InChIKey=HCXBCXWTHARZRI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 545254   

TargetEukaryotic translation initiation factor 4E-binding protein 1(Human)
Effector Therapeutics

US Patent
LigandPNGBDBM545254(US11286268, Compound 742 | US11286268, Compound 89...)
Affinity DataIC50: 32.5nMAssay Description:eIF4E protein was pre-incubated with EDA-m7GDP-ATTO-550 in FPB at 2xconcentrations for 5 minutes prior to the addition of compounds. Compounds (100x)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2022
Entry Details
US Patent

TargetEukaryotic translation initiation factor 4E-binding protein 1(Human)
Effector Therapeutics

US Patent
LigandPNGBDBM545254(US11286268, Compound 742 | US11286268, Compound 89...)
Affinity DataIC50: 32.5nMAssay Description:eIF4E protein was pre-incubated with EDA-m7GDP-ATTO-550 in FPB at 2xconcentrations for 5 minutes prior to the addition of compounds. Compounds (100x)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2022
Entry Details
US Patent