BDBM555909 3-[2-(1-Cyclopropyl-4,6-difluoro-1,3-benzodiazol-5-yl)ethynyl]-1-[(3S,5R)-5-(methoxymethyl)-1-(prop-2-enoyl)pyrrolidin-3-yl]-5-(methylamino)pyrazole-4-carboxamide::US11345681, Example 78
SMILES: CNc1c(C(N)=O)c(nn1[C@H]1C[C@H](COC)N(C1)C(=O)C=C)C#Cc1c(F)cc2n(cnc2c1F)C1CC1
InChI Key: InChIKey=YXVDEILMUVTDMK-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 555909 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Fibroblast growth factor receptor 2
(Human) | BDBM555909
 (US11345681, Example 78 | 3-[2-(1-Cyclopropyl-4,6-d...) | GoogleScholar
| UniChem
| | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
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Citation and Details
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More data for this Ligand-Target Pair | |
Fibroblast growth factor receptor 1
(Human) | BDBM555909
 (US11345681, Example 78 | 3-[2-(1-Cyclopropyl-4,6-d...) | GoogleScholar
| UniChem
| | n/a | n/a | 3.80 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
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More data for this Ligand-Target Pair | |
Fibroblast growth factor receptor 2
(Human) | BDBM555909
 (US11345681, Example 78 | 3-[2-(1-Cyclopropyl-4,6-d...) | GoogleScholar
| UniChem
| | n/a | n/a | 3.70 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this Ligand-Target Pair | |
Fibroblast growth factor receptor 2
(Human) | BDBM555909
 (US11345681, Example 78 | 3-[2-(1-Cyclopropyl-4,6-d...) | GoogleScholar
| UniChem
| | n/a | n/a | 23 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this Ligand-Target Pair | |
Fibroblast growth factor receptor 2
(Human) | BDBM555909
 (US11345681, Example 78 | 3-[2-(1-Cyclopropyl-4,6-d...) | GoogleScholar
| UniChem
| | n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this Ligand-Target Pair | |
Fibroblast growth factor receptor 3
(Human) | BDBM555909
 (US11345681, Example 78 | 3-[2-(1-Cyclopropyl-4,6-d...) | GoogleScholar
| UniChem
| | n/a | n/a | 9.30 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this Ligand-Target Pair | |
Fibroblast growth factor receptor 3
(Human) | BDBM555909
 (US11345681, Example 78 | 3-[2-(1-Cyclopropyl-4,6-d...) | GoogleScholar
| UniChem
| | n/a | n/a | 28 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this Ligand-Target Pair | |
Fibroblast growth factor receptor 3
(Human) | BDBM555909
 (US11345681, Example 78 | 3-[2-(1-Cyclopropyl-4,6-d...) | GoogleScholar
| UniChem
| | n/a | n/a | 4.40 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this Ligand-Target Pair | |