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BDBM555909 3-[2-(1-Cyclopropyl-4,6-difluoro-1,3-benzodiazol-5-yl)ethynyl]-1-[(3S,5R)-5-(methoxymethyl)-1-(prop-2-enoyl)pyrrolidin-3-yl]-5-(methylamino)pyrazole-4-carboxamide::US11345681, Example 78

SMILES: CNc1c(C(N)=O)c(nn1[C@H]1C[C@H](COC)N(C1)C(=O)C=C)C#Cc1c(F)cc2n(cnc2c1F)C1CC1

InChI Key: InChIKey=YXVDEILMUVTDMK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 555909   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Fibroblast growth factor receptor 2


(Human)
BDBM555909
PNG
(US11345681, Example 78 | 3-[2-(1-Cyclopropyl-4,6-d...)
GoogleScholar
UniChem
n/an/a<100n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 1


(Human)
BDBM555909
PNG
(US11345681, Example 78 | 3-[2-(1-Cyclopropyl-4,6-d...)
GoogleScholar
UniChem
n/an/a 3.80n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 2


(Human)
BDBM555909
PNG
(US11345681, Example 78 | 3-[2-(1-Cyclopropyl-4,6-d...)
GoogleScholar
UniChem
n/an/a 3.70n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 2


(Human)
BDBM555909
PNG
(US11345681, Example 78 | 3-[2-(1-Cyclopropyl-4,6-d...)
GoogleScholar
UniChem
n/an/a 23n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 2


(Human)
BDBM555909
PNG
(US11345681, Example 78 | 3-[2-(1-Cyclopropyl-4,6-d...)
GoogleScholar
UniChem
n/an/a 17n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 3


(Human)
BDBM555909
PNG
(US11345681, Example 78 | 3-[2-(1-Cyclopropyl-4,6-d...)
GoogleScholar
UniChem
n/an/a 9.30n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 3


(Human)
BDBM555909
PNG
(US11345681, Example 78 | 3-[2-(1-Cyclopropyl-4,6-d...)
GoogleScholar
UniChem
n/an/a 28n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 3


(Human)
BDBM555909
PNG
(US11345681, Example 78 | 3-[2-(1-Cyclopropyl-4,6-d...)
GoogleScholar
UniChem
n/an/a 4.40n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair