BDBM5617 2-(4-methylpiperazin-1-yl)-N-{3-[4-(morpholin-4-yl)phenyl]-4-oxo-2H,4H-indeno[1,2-c]pyrazol-5-yl}acetamide::3-(4-Morpholinophenyl)-5-((4-methylpiperazino)acetamido)indeno[1,2-c]pyrazol-4-one::Indenopyrazole 8h

SMILES CN1CCN(CC(=O)Nc2cccc3-c4n[nH]c(c4C(=O)c23)-c2ccc(cc2)N2CCOCC2)CC1

InChI Key InChIKey=STWGJFWWXVBMEE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 5617   

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM5617(2-(4-methylpiperazin-1-yl)-N-{3-[4-(morpholin-4-yl...)
Affinity DataIC50:  42nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 uM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM5617(2-(4-methylpiperazin-1-yl)-N-{3-[4-(morpholin-4-yl...)
Affinity DataIC50:  190nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 uM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed