BDBM564221 Roche-Dataset for PDE10A, Compound 535

SMILES Cn1nc(cc1NC(=O)c1c(cnn1C)C(=O)N1CCC1)-c1ccccn1

InChI Key InChIKey=NSPOMBFWRXNIDE-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 564221   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
F. Hoffmann-La Roche

LigandBDBM564221(Roche-Dataset for PDE10A, Compound 535)Copy SMILESCopy InChI

Affinity DataIC50: 7.96nMAssay Description:Human PDE10A IC50 values were determined by using purified enzyme (Biomol cat. # SE-534) in a scintillation proximity assay (SPA) in 96 well plates (...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
10/28/2022
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL