BDBM571325 5-{2- acetamidoimidazo [1,2-b]pyridazin- 6-yl}-N-{[(1S, 2S)-2-(4- fluorophenyl) cyclopropyl] methyl}-2-::US11440913, Example 401

SMILES CC(=O)Nc1cn2nc(ccc2n1)-c1ccc(C)c(c1)C(=O)NC[C@H]1C[C@@H]1c1ccc(F)cc1

InChI Key InChIKey=YJWNMTMOJTZFDQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 571325   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM571325(US11440913, Example 401 | 5-{2- acetamidoimidazo [...)
Affinity DataIC50: 105nMAssay Description:A solution was prepared containing 0.2 nM Anti GST-Tb (Cisbio, 61GSTTLB), 90.6 nM probe and 1 nM His-GST-TVMV-hRIPK1(1-324) in FRET Buffer (20 mM HEP...More data for this Ligand-Target Pair
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Date in BDB:
11/19/2022
Entry Details
US Patent