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BDBM5789 3-({4-butoxy-1H-pyrazolo[3,4-b]pyridin-5-yl}carbonyl)pyridine::SQ-67563 Analog 10d::pyrazolo[3,4-b]pyridine deriv.

SMILES: CCCCOc1c(cnc2[nH]ncc12)C(=O)c1cccnc1

InChI Key: InChIKey=KGEZTJJIIIRHSQ-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 5789   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
CDK2/CycE


(Homo sapiens (Human))
BDBM5789
PNG
(3-({4-butoxy-1H-pyrazolo[3,4-b]pyridin-5-yl}carbon...)
Show SMILES CCCCOc1c(cnc2[nH]ncc12)C(=O)c1cccnc1
Show InChI InChI=1S/C16H16N4O2/c1-2-3-7-22-15-12(9-18-16-13(15)10-19-20-16)14(21)11-5-4-6-17-8-11/h4-6,8-10H,2-3,7H2,1H3,(H,18,19,20)
PDB

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.40E+3n/an/an/an/an/an/a



Bristol-Myers Squibb Co.



Assay Description
The enzyme was assayed with substrate in the presence of 25 uM ATP/[gamma-33P] ATP and test compound. Dose response curves were generated to determ...


Bioorg Med Chem Lett 13: 2405-8 (2003)


Article DOI: 10.1016/s0960-894x(03)00381-0
BindingDB Entry DOI: 10.7270/Q2ZS2TPW
More data for this
Ligand-Target Pair