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BDBM58136 MLS000770597::N-(4-pyridin-2-yl-1,3-thiazol-2-yl)-3-(1,2,3,4-tetrazol-1-yl)benzamide::N-(4-pyridin-2-yl-1,3-thiazol-2-yl)-3-(tetrazol-1-yl)benzamide::N-[4-(2-pyridinyl)-2-thiazolyl]-3-(1-tetrazolyl)benzamide::N-[4-(2-pyridyl)thiazol-2-yl]-3-(tetrazol-1-yl)benzamide::SMR000375858::cid_4880352

SMILES: O=C(Nc1nc(cs1)-c1ccccn1)c1cccc(c1)-n1cnnn1

InChI Key: InChIKey=LBULVQIAQUOMQZ-UHFFFAOYSA-N

Data: 2 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 58136   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
streptokinase A precursor


(Streptococcus pyogenes M1 GAS)
BDBM58136
PNG
(MLS000770597 | N-(4-pyridin-2-yl-1,3-thiazol-2-yl)...)
Show SMILES O=C(Nc1nc(cs1)-c1ccccn1)c1cccc(c1)-n1cnnn1
Show InChI InChI=1S/C16H11N7OS/c24-15(11-4-3-5-12(8-11)23-10-18-21-22-23)20-16-19-14(9-25-16)13-6-1-2-7-17-13/h1-10H,(H,19,20,24)
PDB
MMDB

KEGG

UniProtKB/SwissProt

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PC cid
PC sid
UniChem

Similars

PCBioAssay
n/an/an/an/a 1.50E+5n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: Group A streptococcus, GAS, streptokinase, expression, virulence, inhibition, dose response, EC50 Assay Overview: The goal of this assa...


PubChem Bioassay (2009)


BindingDB Entry DOI: 10.7270/Q2736PBV
More data for this
Ligand-Target Pair
Nuclear receptor coactivator 1


(Homo sapiens (Human))
BDBM58136
PNG
(MLS000770597 | N-(4-pyridin-2-yl-1,3-thiazol-2-yl)...)
Show SMILES O=C(Nc1nc(cs1)-c1ccccn1)c1cccc(c1)-n1cnnn1
Show InChI InChI=1S/C16H11N7OS/c24-15(11-4-3-5-12(8-11)23-10-18-21-22-23)20-16-19-14(9-25-16)13-6-1-2-7-17-13/h1-10H,(H,19,20,24)
PDB
MMDB

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KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
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PC cid
PC sid
UniChem

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PCBioAssay
n/an/a 2.25E+4n/an/an/an/an/an/a



The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay


Assay Description
Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...


PubChem Bioassay (2012)


BindingDB Entry DOI: 10.7270/Q2794387
More data for this
Ligand-Target Pair
nuclear receptor coactivator 3 isoform a


(Homo sapiens (Human))
BDBM58136
PNG
(MLS000770597 | N-(4-pyridin-2-yl-1,3-thiazol-2-yl)...)
Show SMILES O=C(Nc1nc(cs1)-c1ccccn1)c1cccc(c1)-n1cnnn1
Show InChI InChI=1S/C16H11N7OS/c24-15(11-4-3-5-12(8-11)23-10-18-21-22-23)20-16-19-14(9-25-16)13-6-1-2-7-17-13/h1-10H,(H,19,20,24)
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
Purchase

PC cid
PC sid
UniChem

Similars

PCBioAssay
n/an/a 2.17E+4n/an/an/an/an/an/a



The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay


Assay Description
Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...


PubChem Bioassay (2012)


BindingDB Entry DOI: 10.7270/Q2C24V0K
More data for this
Ligand-Target Pair