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BDBM5815 3-{4-[4-amino-6-(4-methoxyphenyl)furo[2,3-d]pyrimidin-5-yl]phenyl}-1-[2-fluoro-5-(trifluoromethyl)phenyl]urea::4-amino-5-diarylurea-furo[2,3-d]pyrimidine 2::furo[2,3-d]pyrimidine deriv. 7k
SMILES: COc1ccc(cc1)-c1oc2ncnc(N)c2c1-c1ccc(NC(=O)Nc2cc(ccc2F)C(F)(F)F)cc1
InChI Key: InChIKey=FGZIONRFHVNRJB-UHFFFAOYSA-N
Data: 5 IC50
| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Angiopoietin-1 receptor (Human) | BDBM5815![]() (3-{4-[4-amino-6-(4-methoxyphenyl)furo[2,3-d]pyrimi...) | GoogleScholar | UniChem | n/a | n/a | 2 | n/a | n/a | n/a | n/a | 7.5 | 22 | |
TBA | Citation and Details | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Vascular endothelial growth factor receptor 2 (Human) | BDBM5815![]() (3-{4-[4-amino-6-(4-methoxyphenyl)furo[2,3-d]pyrimi...) | GoogleScholar | UniChem | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Vascular endothelial growth factor receptor 2 (Human) | BDBM5815![]() (3-{4-[4-amino-6-(4-methoxyphenyl)furo[2,3-d]pyrimi...) | GoogleScholar | UniChem | n/a | n/a | 15.5 | n/a | n/a | n/a | n/a | 7.5 | 22 | |
TBA | Citation and Details | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Angiopoietin-1 receptor (Human) | BDBM5815![]() (3-{4-[4-amino-6-(4-methoxyphenyl)furo[2,3-d]pyrimi...) | GoogleScholar | UniChem | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Vascular endothelial growth factor receptor 2 (Human) | BDBM5815![]() (3-{4-[4-amino-6-(4-methoxyphenyl)furo[2,3-d]pyrimi...) | GoogleScholar | UniChem | n/a | n/a | 3.02 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||