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BDBM58189 1-(4-fluorophenyl)-4-[(3-phenyl-1H-pyrazol-4-yl)methyl]piperazine::1-(4-fluorophenyl)-4-[(5-phenyl-1H-pyrazol-4-yl)methyl]piperazine::MLS000834786::SMR000458404::cid_2812426

SMILES: Fc1ccc(cc1)N1CCN(Cc2c[nH]nc2-c2ccccc2)CC1

InChI Key: InChIKey=WRSMRIOWGWHKGT-UHFFFAOYSA-N

Data: 1 EC50

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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 58189   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
streptokinase A precursor


(Streptococcus pyogenes M1 GAS)
BDBM58189
PNG
(1-(4-fluorophenyl)-4-[(3-phenyl-1H-pyrazol-4-yl)me...)
Show SMILES Fc1ccc(cc1)N1CCN(Cc2c[nH]nc2-c2ccccc2)CC1
Show InChI InChI=1S/C20H21FN4/c21-18-6-8-19(9-7-18)25-12-10-24(11-13-25)15-17-14-22-23-20(17)16-4-2-1-3-5-16/h1-9,14H,10-13,15H2,(H,22,23)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
Purchase

PC cid
PC sid
UniChem

Similars

PCBioAssay
n/an/an/an/a 1.50E+5n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: Group A streptococcus, GAS, streptokinase, expression, virulence, inhibition, dose response, EC50 Assay Overview: The goal of this assa...


PubChem Bioassay (2009)


BindingDB Entry DOI: 10.7270/Q2736PBV
More data for this
Ligand-Target Pair