BDBM5832 3-{4-[methyl({2-[(3-sulfamoylphenyl)amino]pyrimidin-4-yl})amino]phenyl}-1-[4-(trifluoromethoxy)phenyl]urea::urea deriv. 23

SMILES: CN(c1ccc(cc1)NC(=O)Nc2ccc(cc2)OC(F)(F)F)c3ccnc(n3)Nc4cccc(c4)S(=O)(=O)N

InChI Key: InChIKey=SNRUTMWCDZHKKM-UHFFFAOYSA-N

Data: 1 IC50  9 Kd

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 5832   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Human)	BDBM5832 (3-{4-[methyl({2-[(3-sulfamoylphenyl)amino]pyrimidi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2	n/a	n/a	n/a	n/a	7.5	22
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Mixed lineage kinase domain-like protein (Human)	BDBM5832 (3-{4-[methyl({2-[(3-sulfamoylphenyl)amino]pyrimidi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	9.30E+3	n/a	n/a	n/a	n/a	n/a
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Receptor-interacting serine/threonine-protein kinase 1 (Human)	BDBM5832 (3-{4-[methyl({2-[(3-sulfamoylphenyl)amino]pyrimidi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	64	n/a	n/a	n/a	n/a	n/a
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Receptor-interacting serine/threonine-protein kinase 3 (Human)	BDBM5832 (3-{4-[methyl({2-[(3-sulfamoylphenyl)amino]pyrimidi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	680	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Mixed lineage kinase domain-like protein (Human)	BDBM5832 (3-{4-[methyl({2-[(3-sulfamoylphenyl)amino]pyrimidi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	530	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Mixed lineage kinase domain-like protein (Human)	BDBM5832 (3-{4-[methyl({2-[(3-sulfamoylphenyl)amino]pyrimidi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	530	n/a	n/a	n/a	n/a	n/a
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Mixed lineage kinase domain-like protein (Mus musculus)	BDBM5832 (3-{4-[methyl({2-[(3-sulfamoylphenyl)amino]pyrimidi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	9.30E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mixed lineage kinase domain-like protein (Human)	BDBM5832 (3-{4-[methyl({2-[(3-sulfamoylphenyl)amino]pyrimidi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	530	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Receptor-interacting serine/threonine-protein kinase 1 (Human)	BDBM5832 (3-{4-[methyl({2-[(3-sulfamoylphenyl)amino]pyrimidi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	64	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Receptor-interacting serine/threonine-protein kinase 3 (Human)	BDBM5832 (3-{4-[methyl({2-[(3-sulfamoylphenyl)amino]pyrimidi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	680	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair