BDBM5891 1-(2-methylphenyl)-3-[4-(1-oxo-2,3-dihydro-1H-isoindol-4-yl)phenyl]urea::CHEMBL360724::isoindolinone analog 4c

SMILES Cc1ccccc1NC(=O)Nc1ccc(cc1)-c1cccc2C(=O)NCc12

InChI Key InChIKey=YKRMRHXPPNGGCU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 5891   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM5891(1-(2-methylphenyl)-3-[4-(1-oxo-2,3-dihydro-1H-isoi...)
Affinity DataIC50:  4.40E+3nMpH: 7.4 T: 2°CAssay Description:The assay was using baculovirus-expressed recombinant protein kinase and biotinylated poly-Glu-Ala-Tyr substrate. HTRF is based on the proximity of a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed