BDBM589988 (R)-1-(4-(6-amino-5-(trifluoromethoxy)pyridin-3-yl)-1-(3-fluorobicyclo[1.1.1]pentan-1-yl)-1H-imidazol-2-yl)-2,2,2-trifluoroethanol::US11560366, Example 1a::US11560366, Example 1b

SMILES: Nc1ncc(cc1OC(F)(F)F)-c1cn(c(n1)[C@@H](O)C(F)(F)F)C12CC(F)(C1)C2

InChI Key: InChIKey=XUOJHVFYSAMHNK-UHFFFAOYSA-N

Data: 6 IC50  2 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 589988   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase kinase kinase 12 (Human)	BDBM589988 (US11560366, Example 1a | (R)-1-(4-(6-amino-5-(trif...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase kinase kinase 12 (Human)	BDBM589988 (US11560366, Example 1a | (R)-1-(4-(6-amino-5-(trif...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase kinase kinase 12 (Human)	BDBM589988 (US11560366, Example 1a | (R)-1-(4-(6-amino-5-(trif...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	107	n/a	n/a	n/a	n/a	n/a	n/a
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Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM589988 (US11560366, Example 1a | (R)-1-(4-(6-amino-5-(trif...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C9 (Human)	BDBM589988 (US11560366, Example 1a | (R)-1-(4-(6-amino-5-(trif...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2D6 (Human)	BDBM589988 (US11560366, Example 1a | (R)-1-(4-(6-amino-5-(trif...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 3A4 (Human)	BDBM589988 (US11560366, Example 1a | (R)-1-(4-(6-amino-5-(trif...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C19 (Human)	BDBM589988 (US11560366, Example 1a | (R)-1-(4-(6-amino-5-(trif...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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