BDBM59163 6789536

SMILES [O-][N+](=O)c1ccc(cc1)N1C(=S)S\C(=C\c2ccc(Sc3ccc(Cl)cc3)o2)C1=O

InChI Key InChIKey=OWBUIZNGKRRUNL-GZTJUZNOSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 59163   

TargetCoagulation factor VIII(Homo sapiens (Human))
University Of Washington

LigandPNGBDBM59163(6789536)
Affinity DataIC50:  5.85E+3nMT: 2°CAssay Description:Inhibition of factor VIII C2 domain.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VIII(Homo sapiens (Human))
University Of Washington

LigandPNGBDBM59163(6789536)
Affinity DataIC50:  5.60E+3nMpH: 7.9Assay Description:Inhibition of factor X activation assay. A commercially available chromogenic assay that measures the rate of factor X activation to measure inhibit...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VIII(Homo sapiens (Human))
University Of Washington

LigandPNGBDBM59163(6789536)
Affinity DataIC50:  4.81E+3nMpH: 8.0Assay Description:Inhibition of factor VIII ELISA. The interaction between factor VIII and PS was measured by using an enzyme-linked immunoadsorbent assay (ELISA).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed