BDBM59194 4-aminothiazole, 2.0

SMILES Nc1nc(Nc2ccc(Cl)cc2)sc1C(=O)c1cccc(c1)N(=O)=O

InChI Key InChIKey=YQRVBHMYUSGXHL-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 59194   

TargetCyclin-dependent kinase 5(Homo sapiens (Human))
Harvard Medical School

LigandPNGBDBM59194(4-aminothiazole, 2.0)
Affinity DataKi:  660nM IC50:  2.00E+3nMAssay Description:Cdk5, 33P-ATP and cofactors were added in the presence of tau protein. The reaction mixture was incubated to allow Cdk5 to transfer 33P from ATP to ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5(Homo sapiens (Human))
Harvard Medical School

LigandPNGBDBM59194(4-aminothiazole, 2.0)
Affinity DataKi:  690nMAssay Description:Cdk5, 33P-ATP and cofactors were added in the presence of tau protein. The reaction mixture was incubated to allow Cdk5 to transfer 33P from ATP to ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed