BDBM59227 Pyrazolopyrimidone analog, RGB-286147
SMILES CC(C)c1nn(-c2c(Cl)cccc2Cl)c2nc(Cc3ccc(OCCO)cc3)[nH]c(=O)c12
InChI Key InChIKey=RSQPNXBTPUXMQN-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 13 hits for monomerid = 59227
Affinity DataIC50: 48nMAssay Description:Inhibition of in vitro kinase activity of purified CDKs.More data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of in vitro kinase activity of purified CDKs.More data for this Ligand-Target Pair
Affinity DataIC50: 839nMAssay Description:Inhibition of in vitro kinase activity of purified CDKs.More data for this Ligand-Target Pair
Affinity DataIC50: 282nMAssay Description:Inhibition of in vitro kinase activity of purified CDKs.More data for this Ligand-Target Pair
Affinity DataIC50: 51nMAssay Description:Inhibition of HCT116 cell proliferation after 72hr of incubation with compounds was determined by SRB Assay.More data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of in vitro kinase activity of purified CDKs.More data for this Ligand-Target Pair
Affinity DataIC50: 754nMAssay Description:Inhibition of GSK3-betaChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 71nMAssay Description:Inhibition of in vitro kinase activity of purified CDKs.More data for this Ligand-Target Pair
Affinity DataIC50: 754nMAssay Description:Inhibition of in vitro kinase activity of purified CDKs.More data for this Ligand-Target Pair
Affinity DataIC50: 71nMAssay Description:Inhibition of Cdk7/H/MAT1Checked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 282nMAssay Description:Inhibition of Cdk6/cyclin D3Checked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of Cdk9Checked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of in vitro kinase activity of purified CDKs.More data for this Ligand-Target Pair