BDBM59516 2-({3-nitro-4-methylbenzoyl}amino)-5-methyl-4-phenylthiophene-3-carboxamide::5-methyl-2-[(4-methyl-3-nitro-benzoyl)amino]-4-phenyl-thiophene-3-carboxamide::5-methyl-2-[(4-methyl-3-nitro-phenyl)carbonylamino]-4-phenyl-thiophene-3-carboxamide::5-methyl-2-[(4-methyl-3-nitrobenzoyl)amino]-4-phenylthiophene-3-carboxamide::5-methyl-2-[[(4-methyl-3-nitrophenyl)-oxomethyl]amino]-4-phenyl-3-thiophenecarboxamide::MLS000538179::SMR000159744::cid_1014820

SMILES Cc1sc(NC(=O)c2ccc(C)c(c2)[N+]([O-])=O)c(C(N)=O)c1-c1ccccc1

InChI Key InChIKey=VWKPTZORZJXFOF-UHFFFAOYSA-N

Data  3 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 59516   

TargetNucleotide-binding oligomerization domain-containing protein 1(Homo sapiens (Human))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM59516(2-({3-nitro-4-methylbenzoyl}amino)-5-methyl-4-phen...)
Affinity DataEC50:  2.00E+4nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetHeat shock factor protein 1(Mus musculus)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM59516(2-({3-nitro-4-methylbenzoyl}amino)-5-methyl-4-phen...)
Affinity DataEC50: <160nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetNuclear receptor coactivator 1(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM59516(2-({3-nitro-4-methylbenzoyl}amino)-5-methyl-4-phen...)
Affinity DataIC50: >3.59E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetNuclear receptor coactivator 3(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM59516(2-({3-nitro-4-methylbenzoyl}amino)-5-methyl-4-phen...)
Affinity DataIC50: >148nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetTumor necrosis factor(Homo sapiens (Human))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM59516(2-({3-nitro-4-methylbenzoyl}amino)-5-methyl-4-phen...)
Affinity DataIC50:  313nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay