BDBM599927 5-(4-amino-5-{[4- (trifluoromethyl)piperidin-1- yl]methyl}pyrrolo[2,1- f][1,2,4]triazin-7-yl)-2- chloro-N-[(3R,4S)-4- fluoro-1-[2-hydroxy-2- (trifluoromethyl)butanoyl] pyrrolidin-3-yl]benzamide::US11618753, Example 1163

SMILES CCC(O)(C(=O)N1C[C@H](F)[C@@H](C1)NC(=O)c1cc(ccc1Cl)-c1cc(CN2CCC(CC2)C(F)(F)F)c2c(N)ncnn12)C(F)(F)F

InChI Key InChIKey=UNSDCUSCFBASIE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 599927   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM599927(US11618753, Example 1163 | 5-(4-amino-5-{[4- (trif...)
Affinity DataIC50: 2.50E+3nMAssay Description:A solution was prepared containing 0.2 nM Anti GST-Tb (Cisbio, 61GSTTLB), 90.6 nM probe and 1 nM His-GST-TVMV-hRIPK1(1-324) in FRET Buffer (20 mM HEP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2023
Entry Details
US Patent