BDBM601251 (S)-N-((S)-2-(dimethylamino)-3-(1H-indazol-5-yl)propyl)-3-phenyl-3-(1-(trifluoromethyl)cyclopropyl)propanamide ::US11634396, Compound 190

SMILES CN(C)[C@H](CNC(=O)C[C@@H](c1ccccc1)C1(CC1)C(F)(F)F)Cc1ccc2n(ncc2c1)S(=O)(=O)c1ccc(C)cc1

InChI Key InChIKey=KIOCFGHQHGGRIZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 601251   

TargetMu-type opioid receptor(Human)
Epiodyne

US Patent
LigandPNGBDBM601251((S)-N-((S)-2-(dimethylamino)-3-(1H-indazol-5-yl)pr...)
Affinity DataIC50: 1.65E+3nMAssay Description:CHO Tag-lite human mOR stable cell line from Cisbio (NCBI accession number: NM_000914.3, Bedford, Mass.) were seeded and grown to approximately 80% c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2023
Entry Details
US Patent