BDBM601439 US11634410, Example 49::[(1R,5S,6S)-3-{2-[(2S)-2- (trifluoromethyl)pyrimidin-4- yl}-3-azabicyclo[3.1.0]hex-6- yl]acetic acid

SMILES C[C@H]1CCN1c1nc(cc(n1)C(F)(F)F)N1C[C@H]2[C@@H](CC(O)=O)[C@H]2C1

InChI Key InChIKey=MDUYWDNWFXSMJJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 601439   

TargetKetohexokinase(Human)
Pfizer

US Patent
LigandPNGBDBM601439(US11634410, Example 49 | [(1R,5S,6S)-3-{2-[(2S)-2-...)
Affinity DataIC50: 2.08E+3nMAssay Description:A 384-well format on a Corning 3653 assay plate is used, and monitored by UV-vis spectroscopy in continuous mode at rt. Compounds were prepared in DM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent