BDBM601440 US11634410, Example 51::{(1R,5S,6s)-3-[5-cyano-6- (difluoromethyl)pyridin-2-yl]- 3-azabicyclo[3.1.0]hex-6- yl}acetic acid

SMILES OC(=O)C[C@H]1[C@@H]2CN(C[C@H]12)c1cc(C(F)F)c(C#N)c(NC2CCC2)n1

InChI Key InChIKey=BSKAODOQCWFTKW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 601440   

TargetKetohexokinase(Human)
Pfizer

US Patent
LigandPNGBDBM601440(US11634410, Example 51 | {(1R,5S,6s)-3-[5-cyano-6-...)
Affinity DataIC50: 150nMAssay Description:A 384-well format on a Corning 3653 assay plate is used, and monitored by UV-vis spectroscopy in continuous mode at rt. Compounds were prepared in DM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent