BDBM60495 US9079913, MI-908

SMILES CC(C)(C)C[C@H]1N[C@H]([C@H](c2cccc(Cl)c2F)[C@@]11C(=O)Nc2cc(Cl)c(F)cc12)C(=O)NC1CC[C@@H](CC1)OC(=O)[C@H](Cc1ccccc1)NC(=O)OC(C)(C)C

InChI Key InChIKey=SJZZHUDRDGTEMW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 60495   

TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Michigan

US Patent
LigandPNGBDBM60495(US9079913, MI-908)
Affinity DataIC50: 1.00E+4nMpH: 7.5Assay Description:The binding affinity of the MDM2 inhibitors was determined using an optimized, sensitive and quantitative fluorescence polarization-based (FP-based) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2014
Entry Details
US Patent